The research group
In 2007, the tumor-stroma ratio (TSR) was discovered by dr. Wilma Mesker from the dept. Surgery of the Leiden University Medical Center (LUMC). Since then, a lot of research and validation studies into TSR has been done all over the world. The UNITED study was designed to review the reproducibility of the scoring method and implementation of the TSR in daily practice.
The daily research group of the study consists of Meaghan Polack (PhD candidate) and Wilma Mesker (Principal Investigator), and is led by head of the dept. Surgery Prof. Rob Tollenaar. They are supported by the Clinical Research Center of the dept. Surgery at the LUMC. Within this research, there is a close collaboration with the dept. Pathology in the LUMC.
Thanks to all our participating centers, the UNITED study has been able to include patients worldwide. Recently, a new collaboration with another study has been set up too, and more centers and patients have been included: The Prospective Dutch CRC cohort (PLCRC). Also, we are included as open study under the Dutch Colorectal Cancer Group (DCCG).
The UNITED study is now also registered on the BBMRI-NL Catalogue, a searchable database containing information on several Dutch bio- and databanks.